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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MMP15
All Species:
22.12
Human Site:
Y548
Identified Species:
54.07
UniProt:
P51511
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P51511
NP_002419.1
669
75807
Y548
R
L
R
M
E
P
G
Y
P
K
S
I
L
R
D
Chimpanzee
Pan troglodytes
XP_001150678
669
75876
Y548
R
L
R
M
E
P
G
Y
P
K
S
I
L
R
D
Rhesus Macaque
Macaca mulatta
XP_001101050
669
75986
Y548
R
L
R
M
E
P
G
Y
P
K
S
I
L
R
D
Dog
Lupus familis
XP_544383
741
83576
Y611
R
L
R
M
E
P
G
Y
P
K
S
I
L
R
D
Cat
Felis silvestris
Mouse
Mus musculus
O54732
657
74647
H544
R
L
R
M
E
P
G
H
P
K
S
I
L
R
D
Rat
Rattus norvegicus
O35548
607
69605
Y521
I
L
K
V
E
P
G
Y
P
R
S
I
L
K
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508107
920
102568
L673
D
L
R
G
I
Q
Q
L
Y
G
T
P
D
G
Q
Chicken
Gallus gallus
XP_417326
565
65155
Y478
R
L
N
V
E
P
G
Y
P
R
S
I
L
K
D
Frog
Xenopus laevis
Q10835
469
53622
V384
L
K
A
I
D
A
A
V
Y
N
K
D
T
G
K
Zebra Danio
Brachydanio rerio
XP_001924042
504
57745
R420
Y
G
Q
G
M
P
E
R
V
D
T
A
V
W
W
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
97.7
81.7
N.A.
87.4
52.1
N.A.
20.3
50.2
31.2
46.9
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.6
98.3
84.3
N.A.
92.2
67.5
N.A.
31.7
64.7
41.7
58.8
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
100
N.A.
93.3
66.6
N.A.
13.3
73.3
0
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
93.3
N.A.
20
93.3
13.3
26.6
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
10
0
0
10
10
0
0
0
0
10
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
10
0
0
0
10
0
0
0
0
10
0
10
10
0
70
% D
% Glu:
0
0
0
0
70
0
10
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
10
0
20
0
0
70
0
0
10
0
0
0
20
0
% G
% His:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% H
% Ile:
10
0
0
10
10
0
0
0
0
0
0
70
0
0
0
% I
% Lys:
0
10
10
0
0
0
0
0
0
50
10
0
0
20
10
% K
% Leu:
10
80
0
0
0
0
0
10
0
0
0
0
70
0
0
% L
% Met:
0
0
0
50
10
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
10
0
0
0
0
0
0
10
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
80
0
0
70
0
0
10
0
0
0
% P
% Gln:
0
0
10
0
0
10
10
0
0
0
0
0
0
0
10
% Q
% Arg:
60
0
60
0
0
0
0
10
0
20
0
0
0
50
0
% R
% Ser:
0
0
0
0
0
0
0
0
0
0
70
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
20
0
10
0
0
% T
% Val:
0
0
0
20
0
0
0
10
10
0
0
0
10
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
10
% W
% Tyr:
10
0
0
0
0
0
0
60
20
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _